Dupuytren’s Disease and Ledderhose Disease produce a non-malignant thickening of the connective tissue in the hands and feet and can be debilitating over time. Treatment options vary depending on the stage of the disease but radiation therapy given in the early stages may slow disease progression and delay more invasive procedures including injections and hand surgery.

Stage Contracture Description Treatment
N 0 degrees Nodules/cords Radiation Therapy
N/1 0-10 degrees Slight contracture Radiation Therapy
1 11-45 deg.  

Hand Surgery

Needle Aponeurotomy

Collagenase Injection
2 46-90 deg.  

Hand Surgery

Needle Aponeurotomy

Collagenase Injection
3 91-135 deg.  

Hand Surgery

Needle Aponeurotomy
4 >135 deg.  

Hand Surgery

Needle Aponeurotomy

 

Rocky Mountain Cancer Centers has experience treating Dupuytren’s and Ledderhose disease

  • Our radiation oncologists will perform physical exams of the palms and/or soles of the feet. Cords and nodules will be carefully outlined.
  • A CT scan will determine depth of disease aiding in the choice of appropriate energy levels for treatment.
  • Radiation treatments usually consist of two (5) fraction courses separated by six weeks. Each treatment takes less than five minutes.

Outcomes

  • Radiation is primarily recommended to prevent contracture in those who are in the early stage of the disease.
  • Treatment may also help alleviate discomfort caused by nodules and cords on the palms and soles of feet.

Working Together With Healthcare Providers

Our doctors work closely with each patient’s healthcare providers to understand the patient’s individual needs. We are committed to communicating and collaborating with healthcare providers throughout the patient’s care to ensure they receive the best possible care.